Tick-borne encephalitis virus NS3 gene expression does not protect mice from homologous viral challenge

Authors
Morozova, OV Maksimova, TG Bakhvalova, VN
Citation
Ov. Morozova et al., Tick-borne encephalitis virus NS3 gene expression does not protect mice from homologous viral challenge, VIRAL IMMUN, 12(4), 1999, pp. 277-280
Citations number
18
Categorie Soggetti
Immunology
Journal title
VIRAL IMMUNOLOGY
ISSN journal
08828245 → ACNP
Volume
12
Issue
4
Year of publication
1999
Pages
277 - 280
Database
ISI
SICI code
0882-8245(1999)12:4<277:TEVNGE>2.0.ZU;2-M
Abstract
Tick-borne encephalitis virus (TBEV) NS3 gene has been subcloned into the e xpression vector pcDNAI and expressed in eukaryotic cells. Immunization of mice with the recombinant plasmid pcDNAI-NS3 induced antibodies against NS3 protein but did not protect from viral challenge.