There are now more than 150 published epidemiologic studies of health effec
ts of particulate air pollution and dozens of related literature reviews. T
his article explores the basic inferences currently being drawn from the li
terature regarding the epidemiologic evidence particulate pollution induced
health effects. Although there is not a complete consensus of opinion, mos
t reviewers conclude that the overall epidemiologic evidence suggests that
particulate air pollution, especially fine combustion-source pollution comm
on to many urban and industrial environments, is an important risk factor f
or cardiopulmonary disease and mortality. Most of the epidemiological effor
t has focused on effects of acute exposure, but effects of chronic exposure
may be more important in terms of overall public health relevance. Some re
viewers contend that long-term, repeated exposure likely increases the risk
of chronic respiratory disease and the risk of cardiorespiratory mortality
. There is more general (but still not unanimous) agreement that shortterm
exposures to particulate pollution can exacerbate existing cardiovascular a
nd pulmonary disease and increase the number of persons in a population who
become symptomatic, require medical attention, or die.