On any given day, more than 700,000 people in the United States receive alc
oholism treatment in either inpatient or outpatient settings. For many of t
hose patients, detoxification-with or without pharmacotherapy-is the first
step of treatment. The major behavioral approaches currently used in alcoho
lism treatment include cognitive-behavioral therapy, motivational enhanceme
nt therapy, and Alcoholics Anonymous (AA) or related 12-step programs. Clin
ical studies, such as the project MATCH trial, have compared the effectiven
ess of these approaches. Overall, that study detected no significant differ
ences among the three treatments in patient outcome, although certain treat
ment methodologies may be most appropriate for patients with certain charac
teristics. Pharmacotherapy with aversive or anticraving medications may sup
plement behavioral treatment approaches. Brief interventions that are deliv
ered by primary health care providers also have been shown to reduce drinki
ng levels, particularly in nondependent drinkers.