Interaction of tea catechins with lipid bilayers was investigated with lipo
some systems, which enabled us to separate liposomes from the external medi
um by centrifugation. we found that epicatechin gallate had the highest aff
inity for lipid bilayers, followed by epigallocatechin gallate, epicatechin
, and epigallocatechin. Epicatechin gallate and epigallocatechin gallate in
the surface of lipid bilayer perturbed the membrane structure.