Albert Woolley and Cecil Roe were healthy, middle-aged men who became parap
legic after spinal anaesthesia for minor surgery at the Chesterfield Royal
Hospital in 1947. The spinal anaesthetics were given by the same anaestheti
st, Dr Malcolm Graham, using the same drug on the same day at the same hosp
ital. The outcome for the patients and their families was devastating, as i
t was for the use of spinal anaesthesia in the UK. At the trial 6 yr later,
and against the opinion of leading neurologists, the judge accepted Profes
sor Macintosh's suggestion that phenol, in which the ampoules of local anae
sthetic had been immersed, had contaminated the local anaesthetic through i
nvisible cracks. In an interview 30 yr after the verdict, Dr Graham believe
d that the tragedy was caused by contamination of the spinal needles or syr
inges during the sterilization process. The subsequent explanation that, on
the day in question, descaling liquid in the sterilizing pan had not been
replaced by water, supported his belief and finally offered a credible expl
anation. We review the Woolley and Roe case, the status of spinal anaesthes
ia before and after 1947, and the relevant medico-legal judgments in claims
for negligence in the early days of the National Health Service.