DNA-PCR system FGA (FIBRA) - Genotype and allele frequencies in a sample of western Germany (Dusseldorf region)

Frequency data for the STR system FGA (HumFibra) were obtained from a Cauca soid German population sample (Dusseldorf area) of 424 unrelated individual s. PCR products were detected by horizontal polyacrylamid gel electrophores is and a total of 16 alleles was identified by side-by-side comparison, wit h a commercially available sequenced ladder. The observed genotype distribu tion showed no significant deviation from the Hardy-Weinberg equilibrium. T he high information content (pooled German data: rate of heterozygosity = 0 .8626; probability of match = 0.0344; mean exclusion chance = 0.7240) rende r this system a useful tool not only in forensic casework (criminal and pat ernity cases) but in population genetics too.