The in vitro methods proposed for estimating calcium bioavailability can be
useful in studying the effect of dietetic factors. The aim of our work was
to study the possible influence of different infant formula components - c
alcium, phosphorus, lactose, citric acid, ascorbic acid and proteins - on c
alcium bioavailability, considering dialysability to be an estimate of bioa
vailability. The 1981 method of Miller et al. with slight modifications (co
ncerted action n degrees 10 - FLAIR project) was applied to 18 commercial i
nfant formulas of six different types: adapted, follow-up, preterm, hydroly
sates, lactose-free and soy-based. Significant positive linear correlations
between the amount of calcium dialysed and the calcium and phosphorus cont
ents were found. However, there were no statistically significant correlati
ons between the amount of calcium dialysed and the lactose, ascorbic acid o
r citric acid contents, In the case of proteins an exponential relationship
was found between the amount of calcium dialysed and the protein content.