Background: Adult mechanical ventilators have traditionally been press
ure- or time-triggered. More recently, flow triggering has become avai
lable and some adult ventilators allow the choice between pressure or
flow triggering, Prior studies have supported the superiority of flow
triggering during continuous positive airway pressure, but few have co
mpared pressure and flow triggering during pressure support ventilatio
n (PSV). The purpose of this study was to compare pressure and flow tr
iggering during PSV in adult mechanically ventilated patients. Methods
: The study population consisted of 10 adult patients ventilated with
a mechanical ventilator (Nellcor-Puritan-Bennett 7200ae) in the PSV mo
de. In random order, we compared pressure triggering of -0.5 H2O, pres
sure triggering -1 cm H2O, flow triggering of 5/2 L/min, and flow trig
gering 10/3 L/min. Pressure was measured for 5 min at the proximal end
otracheal tube using a data acquisition rate of 100 Hz. From the airwa
y pressure signal, trigger pressure (Delta P) was defined as the diffe
rence between positive end-expiratory pressure (PEEP) and the maximum
negative deflection prior to onset of the triggered breath. Pressure-t
ime product (PTP) was defined as the area produced by the pressure wav
eform below PEEP during onset of the triggered breath, Trigger time (D
elta T) was defined as the time interval below PEEP during onset of th
e triggered breath. Results: A pressure trigger of -0.5 cm H2O was sig
nificantly more sensitive than the other trigger methods for Delta P,
PTP, and Delta T (p<0.001), There was also a significant difference be
tween patients for Delta P, Delta T, and PTP for each trigger method (
p<0.001). Conclusions: For this group of patients, flow triggering was
not superior to pressure triggering at -0.5 cm H2O during PSV.