Primary MALT lymphoma of the kidney

Citation
M. Colovic et al., Primary MALT lymphoma of the kidney, HEM CELL TH, 41(5), 1999, pp. 229-232
Citations number
8
Categorie Soggetti
Hematology,"Cardiovascular & Hematology Research
Journal title
HEMATOLOGY AND CELL THERAPY
ISSN journal
12693286 → ACNP
Volume
41
Issue
5
Year of publication
1999
Pages
229 - 232
Database
ISI
SICI code
1269-3286(199911)41:5<229:PMLOTK>2.0.ZU;2-F
Abstract
A primary mucosa associated lymphoid tissue tumor (MALT) of the kidney in a 50-year-old man who suffered from on therapy resistent high blood pressure over 15 years period is presented. A mass in the right kidney (6x5x3 cm) d uring routine check up was discovered on ultrasonography and confirmed on C T scan and NMR. The patient was submitted to nephrectomy. A mass involving kidney, pyelon and upper part of the meter was found. Histology showed low grade non-Hodgkin B-cell lymphoma of MALT type. The neoplastic cells were p ostitive for monoclonal antibodies CD20, CD79 alpha, surface and cytoplasmi c and IgM immunoglobulins and showed light chain restriction (kappa(+)). Af ter histology was available, a careful staging was performed. The disease w as not found anywhere else. It was concluded that the patient belonged to t he stage IE of primary kidney MALT lymphoma. Gastroscopy showed signs of ch ronic superficial gastritis. Urease test was positive and IgG antibodies ag ainst Helicobacter pylori in titer 421 were found as well. Except for Helic obacter pylori no additional therapy was given.