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Synthesis of optically active 2-piperidylglycine
Authors
Chung, HK
Kim, HW
Chung, KH
Citation
Hk. Chung et al., Synthesis of optically active 2-piperidylglycine, HETEROCYCLE, 51(12), 1999, pp. 2983-2989
Citations number
15
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 →
ACNP
Volume
51
Issue
12
Year of publication
1999
Pages
2983 - 2989
Database
ISI
SICI code
0385-5414(199912)51:12<2983:SOOA2>2.0.ZU;2-Q
Abstract
Both chiral threo- and erythro-2-piperidylglycines were synthesized hem rac emic 2-[(N-benzyloxycarbonyl)piperidin-2-yl]ethanoic acid. (4S,5S)-4 -Methy l-5-phenyl-2-oxa-zolidinone was us ed as a chiral auxiliary in the resoluti on and azidation.