Evaluation of low serum vitamin B-12 in the non-anaemic pregnant patient

Low serum vitamin B-12 concentrations in pregnancy may not indicate true me galoblastic anaemia. In the present study we compared biochemical indices o f vitamin B-12 deficiency (serum homocysteine and urine methylmalonic acid) in non-anaemic pregnant women with and without low serum vitamin B-12 conc entrations. The groups were matched for age, parity and gestational age. No differences were found, and ail values were within normal range. These res ults suggest that the measurement of low ser um B-12 concentrations in preg nant women should he followed by analysis at the biochemical level before v itamin B-12 injections are started.