Chromoblastomycosis in India

Background Four patients with chromoblastomycosis are presented. An additio nal 30 infected Indian patients are reviewed. Results These 34 patients ranged in age from 12 to 80 years with a male to female ratio of 5.8 : 1. Onset before the age of 20 years was seen in 24% o f cases which was comparatively high. Culture was positive in 72% of cases and sclerotic bodies were observed in 84% of cases. A relatively higher pre valence (15%) of Fonsecaea compacta was observed. Unusual cutaneous sites a fflicted were the penile shaft, vulva, and ala of the nose, and unusual ext racutaneous spread was seen in the pleural cavity, ileocecal region, laryng otracheal area, and tonsils. Extracutaneous involvement was seen in 24% of cases. Overlapping infection with another fungus, Geotrichum candidum, was seen in one case. Conclusions Combination therapy with two azoles was attempted with some suc cess for clinical cure.