MITOCHONDRIAL CARDIOMYOPATHY - MOLECULAR AND BIOCHEMICAL-ANALYSIS

Abnormalties in cardiac mitochondrial respiratory enzymes and mitochon drial DNA have been found in an increasing number of pediatric cases o f both dilated and hypertrophic cardiomyopathy, giving rise to the ent ity known as mitochondrial cardiomyopathy. Histochemical, biochemical, and molecular findings are described in this review of mitochondrial cardiomyopathy, which should provide assistance in its diagnostic iden tification.