T. Watanabe et al., Brady-tachycardia syndrome after radiotherapy for lung cancer - Assessmentby computed tomography and carbon-11 methionine positron emission tomography, JPN HEART J, 40(5), 1999, pp. 677-681
A 74-year-old male who had received radiotherapy (total 54 Gy) for right lu
ng cancer 7 months earlier developed a symptomatic brady-tachycardia syndro
me requiring the implantation of a permanent pacemaker. Chest CT showed a p
ulmonary tumor of 2-cm diameter in the right lower lobe with direct extensi
on into the surrounding tissue, suggesting the possibility of cardiac invas
ion. Carbon-ii methionine positron emission tomography (PET) indicated the
absence of visible invasion of the beast with lung cancer. The brady-tachyc
ardia syndrome, therefore, was considered to be associated with sinus node
injury due to radiation. Carbon-ii methionine PET metabolic imaging might p
lay an important role in evaluating noninvasively the cause of the arrhythm
ia in this patient.