In recent years, encephalopathy has increasingly been recognized as a compl
ication of Hashimoto's thyroiditis. It can begin abruptly as a stroke-like
event, acute seizures, or confusion, or as an insidious decline in cognitiv
e function. Most reported cases have been on adult patients, although this
encephalopathy does affect children as well. This form of encephalopathy sh
ould be considered in the differential diagnosis of children and adults wit
h unexplained neurologic deterioration. We describe the case of a child in
whom acute encephalopathy was the presenting symptom of Hashimoto's thyroid
itis.