Laparoscopic management of a variety of renal diseases has assumed an incre
asingly important role as an alternative to open surgery. At many instituti
ons, the transperitoneal approach has been the more commonly employed techn
ique because it creates a larger working space and reveals easily recognize
d landmarks, At the Cleveland Clinic, however, laparoscopic simple nephrect
omy for benign disease and laparoscopic radical nephrectomy for cancer are
preferentially approached retroperitoneoscopically. Herein, we present our
technique of retroperitoneal laparoscopic nephrectomy.