A chemoenzymatic synthesis of aromatic carboxylic acid vinyl esters

Authors
Ishihara, K Nakajima, N Itoh, T Yamaguchi, H Nakamura, K Furuya, T Hamada, H
Citation
K. Ishihara et al., A chemoenzymatic synthesis of aromatic carboxylic acid vinyl esters, J MOL CAT B, 7(5-6), 1999, pp. 307-310
Citations number
10
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
ISSN journal
13811177 → ACNP
Volume
7
Issue
5-6
Year of publication
1999
Pages
307 - 310
Database
ISI
SICI code
1381-1177(199912)7:5-6<307:ACSOAC>2.0.ZU;2-U
Abstract
The practical synthesis of vinyl p-coumarate (vinyl 4-hydroxycinnamate) and vinyl ferulate (vinyl 4-hydroxy-3-methoxycinnamate) was accomplished via a transesterification to the corresponding aromatic acid using vinyl acetate and a catalytic amount of PdCl2, followed by the lipase-cataIyzed regiosel ective alcoholysis in EtOH. (C) 1999 Elsevier Science B.V. All rights reser ved.