In this article, some aspects of the phenomenon of infantile colic or fussi
ng and crying behavior in early infancy are reviewed. The major points addr
essed are as follows: 1) evidence that infants with colic differ significan
tly in their pattern of distressed behavior from noncolicky infants; 2) the
evidence of colic in children with known food allergy; 3) the incidence of
food allergy in children with colic, 4) the outcome of trials focusing on
the dietary management of colic; 5) the outcome of studies involving behavi
or modification in colic; 6) the outcome of a preliminary trial of modifica
tion of maternal diet in very young infants with colic; and 7) findings of
a systematic review of different treatments for colic.