Vaginally applied diquat intoxication

Citation
J. Rudez et al., Vaginally applied diquat intoxication, J TOX-CLIN, 37(7), 1999, pp. 877-879
Citations number
12
Categorie Soggetti
Pharmacology,"Pharmacology & Toxicology
Journal title
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY
ISSN journal
07313810 → ACNP
Volume
37
Issue
7
Year of publication
1999
Pages
877 - 879
Database
ISI
SICI code
0731-3810(1999)37:7<877:VADI>2.0.ZU;2-Q
Abstract
Case Report: We report the case of a woman who introduced 20 mL of diquat c oncentrate intravaginally. Abdominal pain, vomiting, diarrhea, burning ches t pains, and somnolence appeared within the first 24 hours. The vulva and v agina were corrosively inflamed. Acute renal failure appeared on the third day and was treated by 6 hemodialyses over 6 days. The patient was dysarthr ic with spastic tetraparesis for 3 months. The electroencephalogram, diffus ely slow on day 3, was normal on day 28. The electromyoneurogram was normal at all times. Biopsy of a peripheral nerve performed on day 57 following i ntoxication showed no myelin or axonal alterations.