Series of grand mal seizures after consumption of Ecstasy

The consumption of the jet set drug Ecstasy (3,4-methylenedioxymetamphetami ne, abbreviated to MDMA) by young people is increasing markedly. Parallel t o this developement, there is a large number of reports on severe neurologi cal, psychiatric and medical complications following the use of Ecstasy Sei zures are among the most common clinical complications of the CNS following the ingestion of Ecstasy. Our report presents the case of a 21-year-old patient, who had a series of grand mal seizures after taking 12 tablets of Ecstasy. 36 hours after inges tion the substance MDMA was demonstrated at a level of 300 ng/ml in the ser um and CSF. Following treatment with Clonazepam and under an adequate level of carbamazepine, no further seizures occurred. The diagnosis was difficul t because the patient initially denied the consumption of drugs and the rou tine toxicological screening does not contain the substance MDMA.