HEAD AND NECK MANIFESTATIONS OF PLASMA-CELL NEOPLASMS

Multiple myeloma, solitary plasmacytoma of bone, and extramedullary pl asmacytoma are plasma cell neoplasms, They represent distinct manifest ations of a disease continuum, whereby the clinical findings are criti cal to diagnosis, Plasma cell neoplasms are histologically similar, an d distinguishing one from the other has significant implications for t reatment and survival. Plasma cell neoplasms are relatively unusual ma lignancies of the head and neck, region. We present a case series of p lasma cell neoplasms involving the skull base, paranasal sinus, larynx , and mandible as an introduction to a complete review of the literatu re on plasma cell neoplasms of the head and neck area.