Antimicrobial activity of substituted azoles and their nucleosides

Authors
Stefanska, JZ Gralewska, R Starosciak, BJ Kazimierczuk, Z
Citation
Jz. Stefanska et al., Antimicrobial activity of substituted azoles and their nucleosides, PHARMAZIE, 54(12), 1999, pp. 879-884
Citations number
27
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHARMAZIE
ISSN journal
00317144 → ACNP
Volume
54
Issue
12
Year of publication
1999
Pages
879 - 884
Database
ISI
SICI code
0031-7144(199912)54:12<879:AAOSAA>2.0.ZU;2-O
Abstract
Four new 2'-deoxynucleosides of benzimidazole derivatives were prepared. An timicrobial activity of many indazole, benzotriazole, benzimidazole derivat ives and their nucleosides were tested by the agar diffusion method. Among the investigated compounds, dinitro- and trifluoromethyl-substituted benzim idazoles and their nucleosides were the most potent.