Phenylethanoid and cardioactive glycosides from Digitalis ferruginea

From the aerial parts of Digitalis ferruginea ssp. Sen ferruginea (syn. D. aurea Lindley), the phenylethanoid glycoside 1 was isolated in addition to three cardioactive glycosides, lanatosides A (2), C (3) and glucogitoroside (4). For the structure elucidation of the compounds, 1D and 2D-NMR ([LR-]C OSY, HETCOR, NOESY) and MS techniques (ESI-MS and ESI-MS', DCI-NH3-MS, MALD I-TOF) were used. The structure of the new compound 1 was established as 3- hydroxy,4-methoxy-beta-phenylethoxy-3,6-di-O-(alpha-rhamnopyranosyl)-4-O-E- feruloyl-beta-glucopyranoside.