Isolation and structure elucidation of sabadelin, an acetogenin from rootsof Annona muricata

Authors
Gleye, C Laurens, A Laprevote, O Serani, L Hocquemiller, R
Citation
C. Gleye et al., Isolation and structure elucidation of sabadelin, an acetogenin from rootsof Annona muricata, PHYTOCHEM, 52(8), 1999, pp. 1403-1408
Citations number
19
Categorie Soggetti
Agricultural Chemistry","Animal & Plant Sciences
Journal title
PHYTOCHEMISTRY
ISSN journal
00319422 → ACNP
Volume
52
Issue
8
Year of publication
1999
Pages
1403 - 1408
Database
ISI
SICI code
0031-9422(199912)52:8<1403:IASEOS>2.0.ZU;2-X
Abstract
A new acetogenin, sabadelin, has been isolated from the roots of Annona mur icata and was characterised using tandem mass spectrometry (MS/MS). The str ucture determination of this compound was strengthened by epoxidation and t ransformation leading to a known mono-tetrahydrofuran acetogenin. Sabadelin is probably an intermediate in the biosynthetic pathway of mono-THF acetog enins, and it is proposed as a biogenetic precursor of cis-panatellin. (C) 1999 Elsevier Science Ltd. All rights reserved.