Three rearranged 2(3 -> 20) abeotaxanes from the bark of Taxus mairei

Three new rearranged 2(3 --> 20)abeotaxane diterpenoids were isolated from the bark of the Chinese yew, Taxus mairei. Their structures were establishe d as 2 alpha,5 alpha,7 beta,13 alpha-tetraacetoxy-10 beta-hydroxyl-2(3-->20 )abeotaxan-9-one; 7 beta,13 alpha-diacetoxyl-2 alpha,5 alpha,10 beta-trihyd roxyl-2(3 --> 20)abeotaxan-9-one and 2 alpha,7 beta-diacetoxy-5 alpha,10 be ta,13 alpha-trihydroxy1-2(3 --> 20)abeotaxane-9-one on the basis of 1D and 2D NMR data. This is the first example of rearranged 2(3 --> 20)abeotaxanes were isolated from Taxus mairei. (C) 1999 Elsevier Science Ltd. All rights reserved.