Two macrocyclic spermine alkaloids from Aphelandra fuscopunctata (Acanthaceae)

Authors
Youhnovski, N Filipov, S Linden, A Guggisberg, A Werner, C Hesse, M
Citation
N. Youhnovski et al., Two macrocyclic spermine alkaloids from Aphelandra fuscopunctata (Acanthaceae), PHYTOCHEM, 52(8), 1999, pp. 1717-1723
Citations number
20
Categorie Soggetti
Agricultural Chemistry","Animal & Plant Sciences
Journal title
PHYTOCHEMISTRY
ISSN journal
00319422 → ACNP
Volume
52
Issue
8
Year of publication
1999
Pages
1717 - 1723
Database
ISI
SICI code
0031-9422(199912)52:8<1717:TMSAFA>2.0.ZU;2-E
Abstract
Using HPLC-UV(DAD)-MS the MeOH/H2O/HOAc extract of the roots of Aphelandra fuscopunctata (Acanthaceae) was analyzed. The known alkaloid (+)-aphelandri ne and two new macrocyclic spermine alkaloids of the (+)-aphelandrine type were isolated, namely (+)-N(6)-hydroxy-aphelandrine and (+)-N(6)-acetoxy-ap helandrine. Their constitutions and absolute configurations were establishe d. (+)-N(6)-Hydroxy-aphelandrine was obtained from (+)-aphelandrine and (+) -N(6)-acetoxy-aphelandrine. (C) 1999 Elsevier Science Ltd. All rights reser ved.