Three withanolides from Withania coagulans

Authors
Atta-ur-Rahman,"Shabbir, M Yousaf, M Qureshi, S e-Shahwar, D Naz, A Choudhary, MI
Citation
M. Atta-ur-rahman,"shabbir et al., Three withanolides from Withania coagulans, PHYTOCHEM, 52(7), 1999, pp. 1361-1364
Citations number
8
Categorie Soggetti
Agricultural Chemistry","Animal & Plant Sciences
Journal title
PHYTOCHEMISTRY
ISSN journal
00319422 → ACNP
Volume
52
Issue
7
Year of publication
1999
Pages
1361 - 1364
Database
ISI
SICI code
0031-9422(199912)52:7<1361:TWFWC>2.0.ZU;2-5
Abstract
Three new withanolides, coagulins P, Q and R, were isolated from the whole plant of Withania coagulans. Their structures were determined as 20,27-dihy droxy-3 beta-(O-beta-D-glucopyranosyl)-1-oxo-(20S,22R)-witha-5,14,24-trieno lide, 1 alpha,20-dihydroxy-3 beta-(O-beta-D-glucopyranosyl)-(20S,22R)-witha -5,24-dienolideand 3 beta,17 beta-dihydroxy-14,20-epoxy-1-oxo-(22R)-witha-5 ,24-dienolide by a combination of 1D- and 2D-NMR and mass spectroscopic stu dies. (C) 1999 Elsevier Science Ltd. All rights reserved.