Poly(beta-malic acid) derivatives with non-charged hydrophilic lateral groups: synthesis and characterization

Authors
Barbaud, C Cammas-Marion, S Guerin, P
Citation
C. Barbaud et al., Poly(beta-malic acid) derivatives with non-charged hydrophilic lateral groups: synthesis and characterization, POLYM BULL, 43(4-5), 1999, pp. 297-304
Citations number
21
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
POLYMER BULLETIN
ISSN journal
01700839 → ACNP
Volume
43
Issue
4-5
Year of publication
1999
Pages
297 - 304
Database
ISI
SICI code
0170-0839(199911/12)43:4-5<297:PADWNH>2.0.ZU;2-8
Abstract
Poly((3-hydroxypropyl beta malate) has been synthesized starting from aspar tic acid and benzyloxy-1-propanol as precursors. This new polymer was chara cterized by H-1 and C-13 NMR, size exclusion chromatography and differentia l scanning calorimetry. Homopolymer is soluble in water. Two kinds of amphi philic copolymers were also prepared and characterized. Such polymers have been synthesized with a view to preparing non-charged degradable associatin g networks or drug carriers.