M. Jayabalan et al., Synthesis of hydrolytically stable low elastic modulus polyurethane-urea for biomedical applications, POLYM INT, 49(1), 2000, pp. 88-92
Polyurethane-urea without ether linkages was synthesised using dicyclohexyl
-methane diisocyanate (SMDI), hydroxy-terminated polybutadiene (HTPBD) and
m-phenylenediamine (PDA). The hydrolytic stability of this polymer was inve
stigated under in vitro conditions using Ringer's solution and phosphate-bu
ffered saline, and the stability of candidate polyurethane-urea polymers wa
s compared with that of polyurethane prepared with SMDI, HTPBD and I,4-buta
nediol [BD]. The change of tensile properties, hardness and surface propert
ies in the aged polymer is significant for polyurethane when compared with
those of polyurethane-urea polymer. The in vitro study revealed possible ap
plications of polyurethane-urea for long-term biomedical applications. (C)
2000 Society of Chemical Industry.