Synchronous primary carcinoma of the ovary and endometrium. Three case-reports

Simultaneous development of multiple tumors of the female genital tract is a well documented possibility The most common combination is endometroid ca rcinoma of the ovary and adenocarcinoma of the endometrium. This situation occurs in about 10 to 25% of all endometroid carcinomas of the ovary and ca n reflect the presence of either two primaries or of a primary and its meta stasis. Three cases in women aged 70, 56, and 43 years are reported. In all three cases, the endometroid carcinoma of the ovary was diagnosed first, a nd examination of the hysterectomy specimen showed a well differentiated ad enocarcinoma of the endometrium with limited invasion. The objective of thi s article is to discuss the histogenesis of these tumors and their classifi cation as primaries or metastases.