Resolution of racemic 2-amino-1-butanol with immobilised penicillin G acylase

Authors
Fadnavis, NW Sharfuddin, M Vadivel, SK
Citation
Nw. Fadnavis et al., Resolution of racemic 2-amino-1-butanol with immobilised penicillin G acylase, TETRAHEDR-A, 10(23), 1999, pp. 4495-4500
Citations number
25
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
23
Year of publication
1999
Pages
4495 - 4500
Database
ISI
SICI code
0957-4166(199912)10:23<4495:ROR2WI>2.0.ZU;2-T
Abstract
Racemic 2-amino-1-butanol has been resolved to obtain (S)-2-amino-1-butanol with >99% e.e. via enantioselective hydrolysis of its N-phenylacetyl deriv ative with penicillin G acylase immobilised on Eupergit C. (C) 1999 Elsevie r Science Ltd. All rights reserved.