Absolute configuration of alpha-phthalimido carboxylic acid derivatives from circular dichroism spectra

Authors
Skowronek, P Gawronski, J
Citation
P. Skowronek et J. Gawronski, Absolute configuration of alpha-phthalimido carboxylic acid derivatives from circular dichroism spectra, TETRAHEDR-A, 10(23), 1999, pp. 4585-4590
Citations number
29
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
23
Year of publication
1999
Pages
4585 - 4590
Database
ISI
SICI code
0957-4166(199912)10:23<4585:ACOACA>2.0.ZU;2-X
Abstract
It is demonstrated that the Cotton effects due to the 220 nm phthalimide pi -pi* transition observed for a series of derivatives of alpha-phthalimidoca rboxylic acids unequivocally reflect the amino acid absolute configuration. This method is based on the exciton coupling of the allowed transitions of the phthalimide and the carboxylic acid derivative chromophores. (C) 1999 Elsevier Science Ltd. All rights reserved.