Introduction: Diagnosis of Guillian-Barre Syndrome usually is not difficult
, but diagnostic failure occurs for the variable initial presentation. Diag
nosis is based on physical examination showing loss of motor strengh in mor
e than one limb and loss of deep tendon reflexes. Ventilatory assistance, p
harmacologic maintenance of cardiovascular homeostasis, corticosteroids, Ig
G and plasma exchange are the dominant therapeutic measures. Case: This art
icle reports on a case of a 59-year old surgeon suffering from degenerative
disc disease in the lumbar spine. The patient developed a severe course of
the Guillian-Barre Syndrome with persisting motor weakness of the legs. Co
nclusion: If the primary problem at presentation is limb and back pain the
pathology appears to be in the musculoskeletal rather than in neurological
system. The awareness of this presentation of Guillian-Barre-Syndrome will
eliminate delay in diagnosis.