Background. To evaluate the effectiveness and safety of a technique for the
rmal endometrial ablation.
Method. The study was carried out in three steps; step I on 10 fresh uterin
e specimens, step II on 14 intact uteri during hysterectomy and step III in
Eve patients, two weeks prior to hysterectomy. A simple device comprising
a Foley catheter No. I4F, a three way cannula and a 20 cc syringe was used
for the procedure. The balloon of the catheter was inflated within the uter
ine cavity with boiling normal saline for 9 minutes. Uterine cavity and ser
osal temperature was recorded during the procedure. Thermal injury was asse
ssed by gross and histological examination of the specimens.
Results. The mean maximum endometrial cavity temperature was 91 degrees C w
hereas serosal temperatures in steps I and II were 34 degrees C and 35.9 de
grees C respectively. None of the balloons ruptured in any of the steps and
there were no complications. In 13 of 14 specimens in step II, there was a
zone of hyperemia with a depth of 3 to 7 mm. The corresponding histologica
l picture was extensive hemorrhage and fragmentation of glands throughout t
he endometrium including the cornual regions. Consistent findings were note
d in step III in which all but one showed extensive coagulative necrosis of
the whole of endometrium with edema of the underlying myometrium. There wa
s a statistically significant positive correlation between the volume of fl
uid injected and depth of hyperemia.
Conclusion This technique could be a simple, effective, inexpensive and saf
e alternative to hysteroscopic endometrial ablation.