BACKGROUND: A simple new device is proposed for safe and very fast epi
thelial removal of the cornea. This is a rotating plastic brush that r
emoves the corneal epithelium within a few seconds under irrigation, w
ithout causing any mechanical damage to the stromal surface. METHODS:
Comparative SEM and TEM studies on rabbit corneas were carried out fol
lowing epithelial removal by rotating brush and by a Beaver knife blad
e. Epithelial removal time and reepithelialization time after photoref
ractive keratectomy were evaluated in a series of 40 human sighted eye
s treated with the brush. RESULTS: The rotating brush-abraded surface
was smoother compared to the blade-abraded one. Additionally, the brus
h provoked no damage to the basal lamina of the rabbit corneal epithel
ium. In human photorefractive keratectomy, the mean time needed for re
moval of the corneal epithelium by the rotating brush was only 3 sec (
range, 2-5 sec). Reepithelialization time following photorefractive ke
ratectomy did not exceed 3 days. CONCLUSION: Experimental and prelimin
ary clinical studies suggest that the new rotating plastic brush is a
safe and fast method for removing the corneal epithelium.