Three-dimensional intravascular ultrasonic volumetric quantification of stent recoil and neointimal formation of two new generation tubular stents

Citation
Ma. Costa et al., Three-dimensional intravascular ultrasonic volumetric quantification of stent recoil and neointimal formation of two new generation tubular stents, AM J CARD, 85(2), 2000, pp. 135-139
Citations number
21
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
85
Issue
2
Year of publication
2000
Pages
135 - 139
Database
ISI
SICI code
0002-9149(20000115)85:2<135:TIUVQO>2.0.ZU;2-9
Abstract
Currently, several different designs of coronary stents are available. Howe ver, only a few of the new generation stents have been investigated in larg e randomized trials. Mechanical behavior of first-generation stents (Palmaz -Schatz, Gianturco-Roubin) may not be applied to the new designs. We invest igated the chronic mechanical behavior (recoil) of 2 stents recently approv ed by the Food and Drug Administration (MULTILINK and NIR). Forty-eight pat ients with single-stent implantation (23 MULTILINK and 25 NIR) were assesse d by means of volumetric 3-dimensional intravascular ultrasound analysis af ter the procedure and at 6-month follow-up. In addition, volumetric assessm ent of neointimal formation wets performed. No significant chronic stent re coil was detected in both groups (Delta MULTILINK stent volume: +5.6 +/- 41 mm(3) [p = NS] and Delta NIR stent volume + 2.1 +/- 26 mm(3) [p = NS]). A similar degree of neointimal formation at 6 months was observed between the 2 stents (MULTILINK 46 +/- 31.9 mm(3) vs NIR 39.9 +/- 27.6 mm(3), p = NS). In conclusion, these 2 second-generation tubular stents did not show chron ic recoil and appeared to promote similar proliferative response after impl antation in human coronary arteries. (C) 2000 by Excerpta Medica, Inc.