Ma. Costa et al., Three-dimensional intravascular ultrasonic volumetric quantification of stent recoil and neointimal formation of two new generation tubular stents, AM J CARD, 85(2), 2000, pp. 135-139
Citations number
21
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Currently, several different designs of coronary stents are available. Howe
ver, only a few of the new generation stents have been investigated in larg
e randomized trials. Mechanical behavior of first-generation stents (Palmaz
-Schatz, Gianturco-Roubin) may not be applied to the new designs. We invest
igated the chronic mechanical behavior (recoil) of 2 stents recently approv
ed by the Food and Drug Administration (MULTILINK and NIR). Forty-eight pat
ients with single-stent implantation (23 MULTILINK and 25 NIR) were assesse
d by means of volumetric 3-dimensional intravascular ultrasound analysis af
ter the procedure and at 6-month follow-up. In addition, volumetric assessm
ent of neointimal formation wets performed. No significant chronic stent re
coil was detected in both groups (Delta MULTILINK stent volume: +5.6 +/- 41
mm(3) [p = NS] and Delta NIR stent volume + 2.1 +/- 26 mm(3) [p = NS]). A
similar degree of neointimal formation at 6 months was observed between the
2 stents (MULTILINK 46 +/- 31.9 mm(3) vs NIR 39.9 +/- 27.6 mm(3), p = NS).
In conclusion, these 2 second-generation tubular stents did not show chron
ic recoil and appeared to promote similar proliferative response after impl
antation in human coronary arteries. (C) 2000 by Excerpta Medica, Inc.