Two cases of focal nodular hyperplasia of the liver: Value of scintigraphywith Tc-99m GSA and positron emission tomography with FDG

Focal nodular hyperplasia (FNH) of the liver is relatively rare, and can be difficult to differentiate from other benign tumors arising in the liver. We describe a 23-year-old woman and a 25-year-old man with FNH. They were h ospitalized for further evaluation of a space-occupying lesion in the liver . Scintigraphy with Tc-99m diethylenetriaminepentaacetic acid galactosyl hu man serum albumin (Tc-99m GSA) revealed increased radioactivity in the tumo r in one patient and radioactivity similar to that in the normal part of li ver in the other. F-18 fluorodeoxyglucose positron emission tomography (FDG -PET) showed uptake similar to that of the normal liver in both patients. F NH was diagnosed on the basis of angiographic findings and histological fin dings in liver biopsy specimens. Our results show that scintigraphy with Tc -99m GSA and FDG-PET may provide information helpful in the diagnosis of FN H.