Nuchal fibroma, or collagenosis nuchae, is a benign soft tissue tumor that
arises from the posterior cervical subcutaneous tissue, with a predilection
for the interscapular and paraspinal regions. Because of its benign clinic
al course and its close histopathologic similarity to other benign head and
neck lesions, this lesion may be misdiagnosed and underreported. The purpo
se of this paper is to review the histopathologic and radiologic findings u
nique to nuchal fibroma, and compare and contrast it to the other soft tiss
ue neoplasms within the clinical differential diagnosis. These include seve
ral benign (elastofibroma, lipoma, fibrolipoma, nodular fasciitis) and rare
malignant entities (fibrosarcoma, liposarcoma, fibromatosis).