Four cases of amoebiasis are described: two symptomatic with intestinal and
hepatic involvement and two asymptomatic, diagnosed in two, heterosexual,
Italian couples. Infection was probably acquired first by the men, via an i
ndirect faecal-oral route, and then transmitted to their partners in the sa
me way. The two amoebic strains isolated, from the woman of one couple and
the man of the other, were characterized by electrophoresis as zymodemes II
alpha - and XIX of Entamoeba histolytica. These four cases emphasise once
more the role of cyst-passers in the spread of infection and the importance
of biochemical identification of the amoebic isolates, enabling more speci
fic treatment.