Acquisition of chloramphenicol resistance by the linearization and integration of the entire staphylococcal plasmid pC194 into the chromosome of Streptococcus pneumoniae

Authors
Widdowson, CA Adrian, PV Klugman, KP
Citation
Ca. Widdowson et al., Acquisition of chloramphenicol resistance by the linearization and integration of the entire staphylococcal plasmid pC194 into the chromosome of Streptococcus pneumoniae, ANTIM AG CH, 44(2), 2000, pp. 393-395
Citations number
17
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
44
Issue
2
Year of publication
2000
Pages
393 - 395
Database
ISI
SICI code
0066-4804(200002)44:2<393:AOCRBT>2.0.ZU;2-I
Abstract
Chloramphenicol resistance in Streptococcus pneumoniae was associated with cat, which has 100% identity with cat(pC194) from Staphylococcus aureus. In verse PCR with primers specific for pC194 confirmed that in some isolates t he entire staphylococcal plasmid was present in the S. pneumoniae chromosom e, with linearization having occurred between cat(pC194) and the origin of replication.