The macrolide-lincosamide-streptogramin B resistance determinant from Clostridium difficile 630 contains two erm(B) genes

Authors
Farrow, KA Lyras, D Rood, JI
Citation
Ka. Farrow et al., The macrolide-lincosamide-streptogramin B resistance determinant from Clostridium difficile 630 contains two erm(B) genes, ANTIM AG CH, 44(2), 2000, pp. 411-413
Citations number
28
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
44
Issue
2
Year of publication
2000
Pages
411 - 413
Database
ISI
SICI code
0066-4804(200002)44:2<411:TMBRDF>2.0.ZU;2-Y
Abstract
The ErmB macrolide-lincosamide-streptogramin B (MLS) resistance determinant from Clostridium difficile 630 contains two copies of an erm(B) gene, sepa rated by a 1.34-kb direct repeat also found in an Erm(B) determinant from C lostridium perfringens. In addition, both erm(B) genes are flanked by varia nts of the direct repeat sequence. This genetic arrangement is novel for an ErmB MLS resistance determinant.