In vitro development of resistance to telithromycin (HMR 3647), four macrolides, clindamycin, and pristinamycin in Streptococcus pneumoniae

Authors
Davies, TA Dewasse, BE Appelbaum, PC
Citation
Ta. Davies et al., In vitro development of resistance to telithromycin (HMR 3647), four macrolides, clindamycin, and pristinamycin in Streptococcus pneumoniae, ANTIM AG CH, 44(2), 2000, pp. 414-417
Citations number
9
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
44
Issue
2
Year of publication
2000
Pages
414 - 417
Database
ISI
SICI code
0066-4804(200002)44:2<414:IVDORT>2.0.ZU;2-3
Abstract
The ability of 50 sequential subcultures in subinhibitory concentrations of telithromycin (HMR 3647), azithromycin, clarithromycin, erythromycin A, ro xithromycin, clindamycin, and pristinamycin to select for resistance was st udied in five macrolide-susceptible and six macrolide-resistant pneumococci containing mefE or ermB. Telithromycin selected for resistance less often than the other drugs.