Agenesis of the corpus callosum: etiology, clinical features, diagnostic methods and prognosis

Agenesis of the corpus callosum is a frequent congenital malformation with many etiologies and clinical features. It can occur as atl isolated defect which is usually sporadic, it is frequently, associated with other malforma tions, genetic syndromes and metabolic disorders. Ante- or postnatal diagno sis must be followed by a cafeful search for etiology, and it raises uncert ain and difficult question with regard to pregnancy continuation and infant development. (C) 1999 Editions scientifiques et medicales Elsevier SAS.