COMPUTER-SIMULATION OF SOME OF THE MOTOR CIRCUITS UNDERLYING PARKINSONS-DISEASE

Many researchers have published functional models of brain structures involved in Parkinson's disease. These models include the primary stru ctures of the basal ganglia and related cortical areas, and have hypot hesized normal and dysfunctional states. Simple computer simulation of the hypothesized excitatory and inhibitory interactions among brain s tructures can be used to evaluate these models. A computer simulation can be programmed to simulate normal function, disease function, and t reatment effects described in published models.