Three dimensional (3D) analysis of the morphological changes induced by 50Hz magnetic field exposure on human lymphoblastoid cells (Raji)

Authors
Lisi, A Pozzi, D Pasquali, E Rieti, S Girasole, M Cricenti, A Generosi, R Serafino, AL Congiu-Castellano, A Ravagnan, G Giuliani, L Grimaldi, S
Citation
A. Lisi et al., Three dimensional (3D) analysis of the morphological changes induced by 50Hz magnetic field exposure on human lymphoblastoid cells (Raji), BIOELECTROM, 21(1), 2000, pp. 46-51
Citations number
22
Categorie Soggetti
Experimental Biology
Journal title
BIOELECTROMAGNETICS
ISSN journal
01978462 → ACNP
Volume
21
Issue
1
Year of publication
2000
Pages
46 - 51
Database
ISI
SICI code
0197-8462(200001)21:1<46:TD(AOT>2.0.ZU;2-E
Abstract
Human Raji B lymphoid cells after exposure for 64 h to a 1 mT (rms) 50 Hz s inusoidal magnetic field showed a reorganization of membrane and cytoskelet al components. Atomic force microscopy in air revealed several modification s in 80% of the exposed cells, such as loss of microvilli-like structures f ollowed by progressive appearance of membrane introflections. This change i n plasma membrane morphology was also accompanied by a different actin dist ribution, as detected by phalloidin fluorescence. These observations suppor t our previous hypothesis that electric and magnetic fields may modify the plasma membrane structure. (C) 2000 Wiley-Liss,Inc.