Stabilization of papain and lysozyme for application to cosmetic products

For cosmetic applications, papain or lysozyme was conjugated to a soluble b iopolymer produced by Schizophyllum commune. Stability of the conjugated en zymes were significantly enhanced, such that more than 90% of the initial a ctivity remained after a month storage at 45 degrees C, even in a cosmetic formulation including various oils and surfactants. Cosmetic lotion contain ing 1% papain conjugate was more effective in exfoliating stratum corneum o f skin than the lotion containing 5% lactic acid, one of the popular exfoli ating agents.