Direct lithiation and alkylation of trifluoromethyl enol ethers having a beta-sulfur substituent

Citation
M. Yoshimatsu et S. Kinoshita, Direct lithiation and alkylation of trifluoromethyl enol ethers having a beta-sulfur substituent, CHEM PHARM, 48(1), 2000, pp. 145-147
Citations number
21
Categorie Soggetti
Chemistry & Analysis
Journal title
CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN journal
00092363 → ACNP
Volume
48
Issue
1
Year of publication
2000
Pages
145 - 147
Database
ISI
SICI code
0009-2363(200001)48:1<145:DLAAOT>2.0.ZU;2-X
Abstract
The direct lithiation and alkylation of beta-sulfur-alpha-trifluoromethyl s ubstituted enol ethers 1-3 proceeded to give the alkylated products 4a-f, 5 , 6a-c in moderate to high yields.