Interstitial deletion of the long arm of chromosome 2: a clinically recognizable microdeletion syndrome?

We report on a boy with an interstitial deletion of the long arm of chromos ome 2 with breakpoints in chromosome bands q23 and q24.3. Main features wer e low-set and malformed ears, digital anomalies and congenital heart defect s, which have also been reported in most of the previously described cases. A comparison of the features of the present patient with those in previous ly reported cases suggests the deletion 2q23q24 to be a clinically recogniz able syndrome. Clin Dysmorphol 9:47-53 (C) 2000 Lippincott Williams & Wilki ns.