Cardiac function in dialysis patients evaluated by Doppler echocardiography and its relation to intradialytic hypotension: A new index combining systolic and diastolic function
K. Furukawa et al., Cardiac function in dialysis patients evaluated by Doppler echocardiography and its relation to intradialytic hypotension: A new index combining systolic and diastolic function, CLIN NEPHR, 53(1), 2000, pp. 18-24
Aim. patients and methods: Cardiac function of 40 patients on maintenance d
ialysis was examined using a new Doppler index combining systolic and diast
olic function. Immediately before dialysis, ultrasonic pulsed Doppler was u
sed to measure right and left ventricular inflow and outflow waveforms. The
sum of the isovolumetric contraction time (ICT) and isovolumetric relaxati
on time (IRT) was calculated by subtracting the ejection time from the inte
rval between the end of an inflow waveform and the start of the next inflow
waveform. The new index was obtained by dividing the sum of the two isovol
umetric times by the ejection time. Cardiac function was evaluated in dialy
sis patients and healthy controls using new indices of the right and left h
eart systems. Results: Indices of the right and left heart systems in dialy
sis patients were significantly higher than those in healthy controls. With
respect to hypotension during dialysis, patients were divided into two gro
ups, a group with decreased blood pressure (group A: 27 patients) and a gro
up with normal blood pressure (group B: 13 patients). Only the left heart s
ystem index in group A was significantly higher. There were no significant
differences in other M-mode Doppler indices between the two groups. Conclus
ion: The new index was a more sensitive evaluator of cardiac function and p
redictor of hypotension during dialysis compared to standard echocardiograp
hic indices.