Although atopic dermatitis is a very common inflammatory skin condition in
children and results in many pediatric healthcare visits, its exact cause i
s unknown. No single laboratory test can reliably diagnose atopic dermatiti
s, but a relatively simple set of diagnostic criteria was recently validate
d for use by practicing physicians. Because existing remedies for atopic de
rmatitis do not cure the disorder, a program of disease control and managem
ent should be pursued. Patients and their caregivers should be advised that
current therapies are primarily preventive and palliative. However, a comp
rehensive plan that includes routine general skin care, medical management
of symptoms, identification and avoidance of aggravating factors (including
psychological factors), and attention to quality-of-life issues can reduce
the occurrence of skin flares. Successful treatment of acute flare-ups can
be achieved with appropriate use of topical corticosteroids, but occasiona
lly children afflicted with severe atopic dermatitis require more intensive
therapies (e.g., ultraviolet light exposure, systemic corticosteroids, and
cyclosporine) that need close physician monitoring. Physicians must remain
mindful of the psychological and quality-of-life burdens imposed on childr
en with atopic dermatitis and their families and tailor treatments to the n
eeds of each individual patient.